ENTIERE IDENTITIES BETWEEN OPHIOCOMINA NIGRA IGKAPPA GENE AND HUMAN IMMUNOGLOBULIN KAPPA LOCUS.NEW ASPECTS OF INVERTEBRATE IGKAPPA GENES (IPA)

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Published: 2020-12-31
DOI: https://doi.org/10.46545/aijcs.v2i1.199
Keywords:
OPHIOCOMINA, HUMAN IMMUNOGLOBULIN

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Michel Leclerc
University of Orleans, France

Abstract

Entiere identities between Invertebrate Ophiocomina nigra IGKappa gene and Human IGK gene are confirmed, in the present work, at the level of immunoglobulin domains (constant and variable). The transcriptome of the Ophuirid : Ophiocomina nigra IGKappa gene was discovered recently(1).Since it was synthesized de novo and cloned in a pUC-GW-Kan plasmid (2) which was a gift of Bo Huang laboratories. The original sequence of the IGKappa gene, after cloning, was the following in 5’-3’ :

Article Details

Issue

Vol. 2 No. 1 (2020)

Section

Original Articles/Review Articles/Case Reports/Short Communications
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biography

Michel Leclerc, University of Orleans, France

Immunology of Invertebrates

Department of Cell Biology, Developmental Biology, Immunology

University of Orleans, France

How to Cite

ENTIERE IDENTITIES BETWEEN OPHIOCOMINA NIGRA IGKAPPA GENE AND HUMAN IMMUNOGLOBULIN KAPPA LOCUS.NEW ASPECTS OF INVERTEBRATE IGKAPPA GENES (IPA). (2020). American International Journal of Cancer Studies , 2(1), 53-55. https://doi.org/10.46545/aijcs.v2i1.199

References

Leclerc, M., Marie, Y., Davoult, D., Jolly, A., de la Grange, P., & Paris, I. G. (2018). A true new gene in ophiocomina nigra: an ophuirid Igkappa gene. J Appl Biotechnol Bioeng, 5(1), 17-18.

Leclerc, M. (2021). Immunol. Lett. Submitted

Hutchinson, A. T., Jones, D. R., Winter, P. M., Tangye, S. G., & Raison, R. L. (2014). Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts. Human immunology, 75(9), 986-990.

Vincent, N et al. (2014). Meta Gene 2, 320-22